ASCL1 Regulates the Expression of the CHRNA5/A3/B4 Lung Cancer Susceptibility Locus
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چکیده
منابع مشابه
ASCL1 regulates the expression of the CHRNA5/A3/B4 lung cancer susceptibility locus.
Tobacco contains a variety of carcinogens as well as the addictive compound nicotine. Nicotine addiction begins with the binding of nicotine to its cognate receptor, the nicotinic acetylcholine receptor (nAChR). Genome-wide association studies have implicated the nAChR gene cluster, CHRNA5/A3/B4, in nicotine addiction and lung cancer susceptibility. To further delineate the role of this gene cl...
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ژورنال
عنوان ژورنال: Molecular Cancer Research
سال: 2010
ISSN: 1541-7786,1557-3125
DOI: 10.1158/1541-7786.mcr-09-0185